Tag Archives: Vascular

Microvascular and Hemorheological disorders during ischemic heart disease

18T. Urdulashvili, M. Mantskava,
N. Momtselidze, N. Narsia,
G. Mchedlishvili.

 

Scientific –Practical Journal ISSN 1512-1291.
Cardilogy and Internal Medicine XXIN4 (VIII) 2004, 9-15.


 

Significance of the hemorheological disorders in development of acute vascular syndromes is presenltky well known, but their role in pathogenesis of chronic ischemic heart disease is not yet sufficiently analyzed. Aim of the present study was investigation of the relationship between the hemorheological, vascular and hemodynamic factors during the ischemic heart disease.

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We investigated 64 patients with ischemic heart disease of functional classes I-IV with and without heart failure. For evaluation of the hemorheological disorders we investigated the most significant symptom, the erythrocyte aggregability, with the Georgian technique” that provided us with direct and quantitative data. In the some patients we investigated the tone of the resistance arteries with an original non-invasive technique. Based on measurement of[/su_animate]

Hemorheological, microvascular and hemodynamic disorders during coronary heart disease

21Urdulashvili T., Momtselidze N.,
Mantskava M., Narsia N.,
Mchedlishvili G.

 


Georgian Med News.  2006; (136):55-7 (ISSN: 1512-0112)Department of Internal Medicine, State Medical University, Tbilisi, Georgia.

 

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Significance of the hemorheological disorders in development of acute vascular syndromes is presently well known, but their role in pathogenesis of chronic coronary heart disease has not been yet sufficiently analyzed. Aim of the present study was the investigation of the relationship between the hemorheological, vascular and hemo-dynamic factors responsible for development of the coronary heart disease. We investigated 64 patients with coronary heart disease of the functional classes I-IV with and without the heart failure.[/su_animate]

The Role of Various Stressors in the Trigger Mechanism of Raynaud’s Disease (Hemorheological and Vascular Reactions)

32

Mantskava M., Momtselidze N.,
Pargalava N.

 

 

I. Beritashvili Center for Experimental Biomedicine, Department of Blood Circulation and Metabolism, Tbilisi, Georgia, 0160.
Acad. N. Bokhua Center of Vascular and Heart Diseases, Tbilisi, Georgia, 0159.

 

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The emergence and spread of stress reactions are provided by the blood circulation system. In its turn, the adequacy of blood circulation depends on the hemorheological and vascular mechanisms. The changeability of their properties appears to be the basis of the increasing of stress stages. From the viewpoint of biophysical reactions, any change and movement occur with the expenditure and accumulation of energy. Higher level of adaptation energy waste and secondary level take place, when a small stressor entails a small expenditure. There is a maximum possible rate of adaptive energy consumption and at this maximum the organism cannot cope with any additional stimulus.[/su_animate]

Role of various stressor in the starting mechanism of an illness of Reynaud (haemo rheological and vascular reactions)

74Мantskava M., Momtselidze N.,
Pargalava N.

The emergence and spread of stress reactions are provided by the blood circulation system. In its turn, the adequacy of blood circulation depends on the hemorheological and vascular mechanisms. The changeability of their properties appears to be the basis of the increasing of stress stages. From the viewpoint of biophysical reactions, any change and movement occur with the expenditure and accumulation of energy. Higher level of adaptation energy waste and secondary level take place, when a small stressor entails a small expenditure.

There is a maximum possible rate of adaptive energy consumption and at this maximum the organism cannot cope with any additional stimulus. At the same time adaptive and stress diseases develop. Let’s consider the duration and manifestation of Raynaud’s disease from the perspective of adaptation diseases and diseases of the third grade, which appears to be the cause of the double stress effect – cold and emotional- physical and psychic. Total of 97 patients with Raynaud’s disease were examined. For a new vision of the problem it was necessary to find out how the streessors of various nature impact the hemoreheological status and vascular resistance.

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For this purpose all the patients were examined for a resistance index of resistive arteries of the hand and the indices of erythrocyte aggregation and deformability. The patients were divided into four subgroups. The first subgroup – the patients after chilblain, the second subgroup – the patients with psychic strerssor, the third subgroup – the patients with prolonged chronic stress, and the fourth subgroup – the patients without the differentiation of the stressors. [/su_animate]

Hemorrhagic shock and stress – cause and effect on the example of violations of hemorheology changes erythrocyte aggregated

75Mantskava M., Momtselidze N.,
Davlianidze L., Mitagvaria N.

 

The emergence and spread of stress reactions are provided by the blood circulation system. In its turn, the adequacy of blood circulation depends on the hemorheological and vascular mechanisms. The changeability of their properties appears to be the basis of the increasing of stress stages. From the viewpoint of biophysical reactions, any change and movement occur with the expenditure and accumulation of energy.

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Higher level of adaptation energy waste and secondary level take place, when a small stressor entails a small expenditure. There is a maximum possible rate of adaptive energy consumption and at this maximum the organism cannot cope with any additional stimulus.  [/su_animate]