Tag Archives: hemorrhagic

Hemorrhagic Shock and Stress – Cause and Consequence of Hemorheology Disturbances on the Example of the Changes in Erythrocyte Aggregation

31Mantskava M., Momtselidze N.,
Davlianidze N., Mitagvaria N.

 


I. Beritashvili Center for Experimental Biomedicine, Department of Blood Circulation and Metabolism,Tbilisi, Georgia, 0160.
 

 

 

 

 

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Stress, being the general reaction of the organism to the physical and psychological effects, accompanies all the
stages of somatic and psychic formation. Hemorrhagic shock occurring at blood loss appears to be a powerful stress for the organism. The origin (emergence) and spread of stress reactions are characterized by the features of the macro-and microcirculation. In stressful situations the crisis of blood circulation affects the functions of hemorheological disorders, as well as appears to be a consequence of the shock. We were the first to combine these two problems.[/su_animate]

Study of hemorheological parameters at hemorrhagic shock

19M. Mantskava, N. Momtselidze,
L. Davlianidze.

 

I.Beritashvili Center I.Beritashvili Center Of Experimental Biomedicine, Tbilisi, Georgia


Nervous system is concerned to be a structure consisted of dynamic glio-neuro-synaptic networks that are able to morphological and functional modulation under external stimuli. Hemorheological shock is a external stimuli and stressor for brain.

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A particular link, which is involved in various stages of hemorheological shock, is blood rheology.biz. The aim of our work was a comprehensive rheological properties of blood: red blood cell aggregation, deformation of erythrocytes, plasma viscosity, hematocrit at different degrees of severity of experimental hemorrhagic shock. [/su_animate]

Stress – cause and effect hemorheological disorders

15Mantskava M., Momtselidze N.

Lambert academic  Publishing ISBN 978-3-659-66518-9), 2014 www.lap-publishing.com  –77 стр.

The book examines various rheological aspects of the different etiology  stress. Hemorrhagic shock occurring at blood loss appears to be a powerful stress for the organism. The origin (emergence) and spread of stress reactions are characterized by the features of the macro-and microcirculation. In stressful situations the crisis of blood circulation affects the functions of hemorheological disorders, as well as appears to be a consequence of the shock. We were the first to combine these two problems.  

There is a maximum possible rate of adaptive energy consumption and at this maximum the organism cannot cope with any additional stimulus. At the same time adaptive and stress diseases develop. Let’s consider the duration and manifestation of Raynaud's disease from the perspective of adaptation diseases and diseases of the third grade, which appears to be the cause of the double stress effect — cold and emotional- physical and psychic.

Sleep apnea is a independent pathology and a powerful stress for the organism. Apnea is a cause of stress and strengthens the body under stress. We propose a new marker for apnea: platelet composes.

Our data in this book have practical significance for biomedicine.

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Study of erythrocyte deformability at hemorrhagic shock

4M. Mantskava, N. Momtselidze,
L. Davlianidze.

 

I.Beritashvili Center of Experimental Biomedicine, 14 Gotua St., Tbilisi, Georgia, 0160.

 

 

 

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The aim of our work was a red blood cell deformation (rheological rheological ) at rheological degrees of severity of experimental hemorrhagic shock. The study of erythrocyte deformability violation and a compulsory monitoring of this physical value deserve more attention of fundamental and applied sciences. The modeling of hemorrhagic shock of different stages was performed in the group of anesthetized animals by means of standard blood discharge from the femoral artery (2,5 ml – first stage of shock; 5 ml – second stage of shock; 5ml – third stage of shock, n=12).[/su_animate]