Tag Archives: hemorheology

Positive Effect of Bemiparin to Blood Flow

71M. Mantskava, N. Momtselidze,
L. Davlianidze, T. Urdulashvili.

 

 

Beritashvili Center of Experimental Biomedicine, Tbilisi, Georgia, 0160, Gotua St., 14, biomedicine.net@gmail.com;
Medical Centre “Medisoni”, Tbilisi, Georgia, 0182, Kaloubani St., 12
t.urdulashvili@yahoo.com.


 

Abstract

Coagulation and hemorheology play a significant role in blood circulation and ensure its trophic function. According to a modern concept it is impossible to develop physiological process if coagulation and blood rheology systems are not within the normal range. In the development of all pat-physiological processes coagulation and hemorheology play compensatory role, which is directed to adequacy and improvement of the tropic function. To study bemiparin we made research in vivo and in vitro systems. And found that bemiparin has a positive effect not only on the coagulation, but also on the rheological properties of blood.

Keywords: Bemiparin, Erythrocyte, Rheology, Microcirculation

Microcirculation, blood rheology status and age-related changes

14Mantskava М., Momtselidze Н.

Bulletin of Medical control center of Affairs of the President of the Republic of Kazakhstan, No. 5, 2015 Materials I of the Euroasian congress of gerontologists. Pp.173-178.
УДК 612.013.1
УДК 612.135

The major link ofpathogeny ofdevelopment ofthe age-related changes is violation ofmicrocirculation and hemorheology. Practically healthy subjects that were subdivided into age-related groups took part in population researches. The 1st group from 35 to 45 (middle age 40.07+4.5, n=15), 2th group from 48 to 55 (middle age 70.6+5.0, n=15). Protocol o f realization o f researches corresponded to Helsinski declaration [2]. All the investigated hemorheology studies: went through the investigated were examined to hemorheologic status o f blood. The o f arespondence o f red corpuscles settled accounts through the apparatus o f texture analysis (Tas- plus, Leitz). In thefirst group the index ofarespondence on “Georgian technique”was equal to 23+4.7%, in the second group to 31+3.3%, in the third group to 34+2.2%, in a fourth group to 36+2.7%. The statistical processing of data showed that in the different age-related groups hemorheologic status differed. был равен 23±4,7%, во второй группе – 31±3,3%, в третьей группе – 34±2,2%, в четвертой группе – 36±2.7%. Violation o f rheological status increased with the increase o f middle age o f subjects, more precisely arespondence of red corpuscles increased as far as growth of middle age in groups age in groups and for certain differedfrom control values. That work showed how much rheological changes are risk-factor of such diseases thatfluctuate with age.

 

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Hemorhoelogical status during periodontitis and without thyroid dysfunction betwen children the age of 11-13

11Beriashvili Sesili Davidovna
 Postdoc; Georgian David the Builder University    
Mantskava Maia Mikhailovna
Associate Prof.; Beritashvili Biomedical Experimental Center, Tbilisi
Momtselidze Nana Gogievna
 Associate Prof.; Beritashvili Biomedical Experimental Center, Tbilisi
Nikolaishvuli Marina
 Associate Prof.; Beritashvili Biomedical Experimental Center, Tbilisi
Tupinashvili Tamar Nodarovna
 Postdoc; Georgian David the Builder University, Tbilisi
Tamasidze Nino Archilovna
Postdoc; Georgian David the Builder University, Tbilisi

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Blood is not a homogeneous (Newtonian) liquid and it is a suspension having suspended particles, it has exceptional features and it is studied by hemorheology. Blood hemorheology plays a significant role in blood circulation and ensuring its trophic function. Changes in rheological properties of blood may cause a slowdown in the flow, establishment of stasis, therefore tissue hypoxia, which is accompanied by a multi-disease and vice versa, the particular structure of blood depends on a local hematocrit, axial flow of erythrocytes and the existence of plasma layer, blood flow structure changes leads to a disorders of its rheological properties.[/su_animate]