Tag Archives: blood

Positive Effect of Bemiparin to Blood Flow

71M. Mantskava, N. Momtselidze,
L. Davlianidze, T. Urdulashvili.

 

 

Beritashvili Center of Experimental Biomedicine, Tbilisi, Georgia, 0160, Gotua St., 14, biomedicine.net@gmail.com;
Medical Centre “Medisoni”, Tbilisi, Georgia, 0182, Kaloubani St., 12
t.urdulashvili@yahoo.com.


 

Abstract

Coagulation and hemorheology play a significant role in blood circulation and ensure its trophic function. According to a modern concept it is impossible to develop physiological process if coagulation and blood rheology systems are not within the normal range. In the development of all pat-physiological processes coagulation and hemorheology play compensatory role, which is directed to adequacy and improvement of the tropic function. To study bemiparin we made research in vivo and in vitro systems. And found that bemiparin has a positive effect not only on the coagulation, but also on the rheological properties of blood.

Keywords: Bemiparin, Erythrocyte, Rheology, Microcirculation

Coparative significance of the principal factors responsible for microcirculatory disirders in type 2 diabetes mellitus

61M. Mantskava, N. Momtselidze,
G. Mchedlishvili, N. Pargalava.

I.Beritashvilis institute of Physiology, Georgian Academy of Sciences, Tbilisi, Georgia
N. Bochua Georgian Center of Angiology and Vascular Surgery, Tbilisi, Georgia


The present study was aimed at investigating the comparative +changes of the two most significant microcirculatory factors if microvascular blood flow, possibly producing severe disorders in blood supply to tissues in the diabetic patients – constriction of resistant arteries and the hemorheological disorders in the patients with the type 2 diabetes mellitus. By using direct quantitative and highly sensitive investigation techniques we found that insulin improves the blood rheological properties in the microcirculation altered during diabetes.

Regional and systemic hemorheological disorders during feet diabetic gangrene

67Nugzar Pargalava, Maya Mantskava,
George Mchedlishvili.


N. Bochua Center of Angiology and Vascular Surgery, 1. Chachava St., 0159, Tbilisi, Georgia.
Microcirculation Research Center, I.Beritashvili Institure of Physiology, 14 Gotua St., 0160, Tbilisi, Georgia.

 

Abstract. We investigated the RBC aggregability in the patients with the foot diabetic gangrene in the venous blood samples taken from the damaged foot before its amputation, as well as from the cubital vein (the systemic circulation). The RBC aggregability was investigated with the “Georgian technique” that is sensitive and provided us with direct and quantitative data.we found that the RBC aggregability was higher by about 20%, in the blood flowing from the gangrenous tissue than in the systemic circulation.

Key words: Microvascular hemorheology, diabetic gangrene, RBC aggregation.

Comparative significance of the principal factors responsible for microcirculatory disorders in type 2 diabetes mellitus

20M. Mantskava, N. Momtselidze,
G. Mchedlishvili, N. Pargalava.

 

The present study was aimed at investigated the comparative changes of the two most significant microcirculatory factors of microvascular blood flow. Possibly producing severe disorders in blood supply to tissues in the diabetic patients – constriction of resistant arteries and the hemorheological disorders in the patients with the type 2 diabetes mellitus.

 

 

Comparative values of erythrocyte aggregability versus other indices of hemorheological disorders in patients with ischemic brain infarcts

22G. Mchedlishvili,  R. Shakarishvili,
N. Momtselidze, L. Gobejishvili,
M. Aloeva,  M. Mantskava.

 


Microcirculation Research Center, I. Beritashvili Institute of Physiology, Tbilisi, Georgia. Clinical hemorheology and microcirculation (Impact Factor: 3.4). 02/2000; 22(1):9-15.
Source: PubMed

Arteriolar resistance and hemorheological disorders related to raynaud’s phenomenon

24George Mchedlishvili, Maia Mantskava, Nugzar Pargalava.
 

Microvascular Research DOI: 10.1006/mvre.2001.2335
Volume 62, Issue 2, September 2001, Pages 190–195.


Abstract

 

Direct beneficial effect of insulin on blood rheological disorders in the microcirculation

27M. Mantskava, N. Pargalava,
G. Mchedlishvili.

 

Clinical hemorheology and microcirculation 2004;30(3-4):431-3.

 


Abstract

Under both the in vivo and in vitro conditions we investigated the insulin effect on the most significant factor disturbing the blood rheological disorders in the microcirculation, the red blood cell aggregability.

 

 

Regional and systemic hemorheological disorders during feet diabetic gangrene.

28N. Pargalava., Maya Mantskava.,
George Mchedlishvili.

 

Clinical hemorheology and microcirculation 2004;30(3-4):457-9.


Abstract

Hemorheological disorders during ischemic brain infarcts in patients with and without diabetes mellitus

29N. Momtselidze., M. Mantskava.,
G. Mchedlishvili.


Clinical hemorheology and microcirculation 2006;35(1-2):261-4.

 


Abstract

 

 

Hemorheological disorders in patients with type 1 or 2 diabetes mellitus and foot gangrene

30M. Mantskava., N. Momtselidze.,
N. Pargalava., G., Mchedlishvili.

 


Clinical hemorheology and microcirculation 2006;35(1-2):307-10.


 

Abstract

 

 

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