Reological disorders with preeclampsia


Mantskava M.,  Momtselidze N.

Berlin, Germany, 18-21 Mach, 2016 (16 World Congress on Human Reproduction)


The aim of the present study is comparison of changes of hemorheological functional condition responsible for blood flow disorders in the microcirculation in physiology pregnancy, pregnancy women with preeclampsia and control group.

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The principal factor of hemoreological was monitored RBC aggregation with the "Georgian technique" that is sensitive and provided us with direct and quantitative data.  We investigated 25 subjects with mean age 25,5±3,4 (physiological first pregnancy, 21 weeks, n=10; first pregnancy with preeclampsia, 21 weeks, n=8; control, n=7). The analysis of the data was performed using statistical [/su_animate]

programs “Origin 4.1” ( Microsoft. Software, Inc) and Microsoft Excel, evaluated Student and criteria Pearson. Protocol of research was adequate Helsinki Declaration. We found that the RBC aggregability was higher by about 20%, in the blood flowing in women with physiology pregnancy than in the systemic circulation women with physiology pregnancy. RBC aggregability was a mean of 4% higher in the pregnancy without preeclampsia than in the healthy controls, and the difference was not reliable.  Our previous research provides practical recommendations.

Therefore, it is especially important to monitor the agregability of erythrocytes at a pregnancy of any form. A correct diagnosis of hemorheological parameters is particularly important for correcting the violations of separate links of the homeostasis, which is an unavoidable cause of pregnancy.


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