Study of erythrocyte deformability at hemorrhagic shock

4M. Mantskava, N. Momtselidze,
L. Davlianidze.


I.Beritashvili Center of Experimental Biomedicine, 14 Gotua St., Tbilisi, Georgia, 0160.




Data show, that index deformability decreases at increase in number of hemorrhagic shock' stage (12% – one subgroup, 13% – second subgroup and 15% – third subgroup). While studying the deformability of erythrocytes, we monitor the rheological parameters that will promote the development of the algorithm of intensive therapy and a diagnosis of massive blood loss, as well as of hemorrhagic shock.

           Hemorrhagic shock appears to be the sequels of a variety of diseases, especially in abdominal surgery and in gynecological departments. In spite of this the mechanism of development of microcirculational disorders as one of the basic links of shock pathogenesis has not been appropriately studied yet. In not so far past shock was viewed only from the aspect of alteration of general hemodynamics. In the present day scientific literature studies are often related only to the intravascular hemocoagulation. From the point of view of blood rheological properties the crucial factors in the microcirculation system are: local hematocrit, erythrocyte aggregability, erythrocyte deformability and plasma viscosity. As regards the erythrocyte deformation, this rheological parameter must cause far graver results in the organs  the diameter of the capillary lumen of which is equal to or less than is the erythrocyte size.


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