Hemorheological disorders in patients with type 1 or 2 diabetes mellitus and foot gangrene

30M. Mantskava., N. Momtselidze.,
N. Pargalava., G., Mchedlishvili.

 


Clinical hemorheology and microcirculation 2006;35(1-2):307-10.


 

Abstract

 

 

The patients were divided into two groups: (a) with type 1 and (b) with type 2 diabetes mellitus. We matched the RBC aggregability indices in both groups of diabetic patients and compared the obtained results with those in the healthy control group. We found that rheological disorders were considerably pronounced. The RBC aggregability index increased by 62 percent (p < 0.001) in type 1 and by 57 percent (p < 0.001) in type 2 diabetic patients as compared to the control group. However, there were insignificant differences of the RBC aggregability changes between the two groups of patients. Therefore we conclude that blood rheological disorders are similar in both types of diabetes mellitus. The disturbed blood fluidity related to the increased RBC aggregability in the microcirculation promotes, in particular, the development of legs gangrene in both types of diabetes mellitus.

 

         

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