A new article in International peer-reviewed journal «SCI-ARTICLES», №54, 2016 , p. 15-20

Mantskava M., Momtselidze H., Urdulashvili V., Lomitashvili H.

According to our research the index of RBC deformability is the most sensitive, informative for estimating blood rheology in gestosis. Deformability of the erythrocyte membrane determines the blood hemorheological status and evaluates the stage of preeclampsia.

Key words: preeclampsia; blood rheologycal status.

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A new article in International Journal «SCI-ARTICLES», №54, 2016, pp.40-60

Mantskava M.

The article set a goal of assessment of microcirculation and blood rheology in patients group with microangiopathy. In the article for the first time a new non-invasive method for study of microcirculation coefficient k.

Key words: coefficient of microcirculation, diabetes mellitus, angiopathy.

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A new article in International Journal «SCI-ARTICLES», №54, 2016, pp.5-10

Momtselidze N., Mantskava M., Urdulashvili T., Narsia N., Gotsadze M., Mchedlishvili T.

Key words: coronary artery disease; heart failure; blood rheologIcal status; microcirculation coefficient.

The article presents the data of blood rheological status, microcirculation coefficient and hemodynamic parameters. The authors introduced the new concept «Blood flow» for clinical cardiology.

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A new article in International Journal «Novation» , 2016, N2, pp. 105-109

Mantskava M., Momtselidze N.

The emergence and spread of stress reactions to provide adequate blood flow, which in turn depends on hemorheological and coagulation mechanisms and with them coherent phenomena. The article describes the qualitative and quantitative evaluation of the adaptation of the resource by changing blood rheology parameters. We have proposed a method of investigation of blood flow by measuring the aggregated red blood cells. We examined aggregated indicator in patients who are prescribed operation on the day of the primary treatment for vascular surgery, as well as the day before the initial examination. It was found that the therapeutic examination (the previous day), and the appointment of the operation of blood hemorheological status changed dramatically. When therapeutically inspection RT = 34,0 ± 2,7; preoperative RT = 42,2 ± 4,5. The norm for this age is considered RT = 22,5 ± 3,7. Consequently, the patient undergoes stress, not only related to the disease and the upcoming surgery, with anesthesia, but also with the emotional mood.

Key words: stress; blood hemorheology; erythrocyte aggregation; blood rheology status

Lomitashvili N., Mantskava M., Urdudashvili N., Urdulashvili T., Mchedlishvili T., Momtselidze N.

 
Preeclampsia, a complication of being a normal pregnancy is high rates of maternal and perinatal mortality. Research work aimed at studying the etiology of preeclampsia oand the introduction of hemorheological tests in applied medicine . This researche has a social and public importance from the standpoint of the theories and methods of different scientific disciplines. The aim of our study was to evaluate the blood rheology in gestosis mild form. According to our research the index of the deformability of red blood cells is the most sensitive, and therefore informative for the evaluation of blood rheology, in gestosis.

Key words: Preeclampsia, blood rheology, RBC deformability.

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Mantskava M., Urdulashvili T., Narsia T., Mchedlishvili T., Мomcelbdze N.

The aim of our study was to find out the linkages between the rheological blood status, vascular changes and intracardiac hemodynamics in heart failure patients with ischemic heart disease. This requires a comprehensive assessment of the mechanisms of regulation of vascular disorders at the level of the microvasculature and myocardial hemodynamics. Interpretation of our data to better understand the pathogenesis of heart failure, as well as to recommend a list of tests, methods that have been reviewed in an article for evaluation of the clinical status of patients.

Key words: heart failure, cardiac output, blood rheology, resistive artery.

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M.M. Mantskava, N.G. Mоmtselidze

The emergence and spread of stress reactions to provide adequate circulation. This depends on hemorheological and coagulation mechanisms and phenomena. The article describes the qualitative and quantitative date abaut the change adaptation energy of the resource by changing blood rheology parameters during related operational intervention emotional stress. We measure the RBC aggregation (blood rheological status) in patients who are scheduled for surgery on the day primary treatment for vascular surgeon and the day before theinitial examination. RBC aggregation index (EAI) was evaluated with the recently developed “Georgian technique” providing us with direct and quantitative data. It was found thatthe therapeuticexamination(previous day)

andthe appointment ofthe operationbloodrheological status changes abruptly. In therapeutic examination EAI=34,0 ± 2,7; preoperative EAI=42,2 ± 4,5. Control for this age: EAI = 22,5±3,7. Therefore, the patient undergoes stress, is not only associated with the disease and the upcoming surgery, with anesthesia, but also with the emotional mood.

Key words: stress,bloodhemorheology, erythrocyte aggregation, bloodrheologystatus

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Mantskava M.M.; Momtselidze N.G.; Urdulashvili T.A.

In modern pharmacology presented insulins different BY DURATION insulin: ultra-fast action, short-acting, intermediate-acting, long-acting insulins and mixed. This makes it possible to construct various circuits for diabet treatment. The aim of our work was to investigate INFLUENCE OF DIFFERENT BY DURATION insulin action on erythrocyte aggregation of red blood cells in patients with type I and type II and in vitro

Key words: insulin; diabetes mellitus, aggregation of red blood cells.

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M. M. Mantskava

I.Beritashvili Center of Experimental Biomedicine, 0160, Tbilisi, Georgia, L.Gotua St.14,

 e-mail: mantskavamaka@rambler.ru

               Annotation. The resistive arteries of blood circulatory system appear to be the subject for indirect diagnostic studies of microcirculatory channel. At not altered levels of general arterial and venous pressure, the blood flow velocity measured in the resistive arteries depends precisely on the state of the relevant resistive arteries, as a result of its branching. We used an ultrasonic device "Dop 8/4" (Germany) with four inputs for probes with built-in self-recorder. According to the dynamics of changes in blood flow velocity in the radial and posterior tibial arteries in all leads after standard ischemia during the development of post-ischemic hyperemia, the state of branching of the resistive arteries, as well as the blood filling of microcirculatory channel can be judged.For description of the reactions of resistive arteries in all leads, which control a peripheral resistance and microcirculation, the coefficient of microcirculation k has been introduced, which appears to be the ratio of the total post-ischemic blood flow to the average volumetric background blood flow.