Monthly Archives: December 2015

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Positive Effect of Bemiparin to Blood Flow

71M. Mantskava, N. Momtselidze,
L. Davlianidze, T. Urdulashvili.



Beritashvili Center of Experimental Biomedicine, Tbilisi, Georgia, 0160, Gotua St., 14,;
Medical Centre “Medisoni”, Tbilisi, Georgia, 0182, Kaloubani St., 12



Coagulation and hemorheology play a significant role in blood circulation and ensure its trophic function. According to a modern concept it is impossible to develop physiological process if coagulation and blood rheology systems are not within the normal range. In the development of all pat-physiological processes coagulation and hemorheology play compensatory role, which is directed to adequacy and improvement of the tropic function. To study bemiparin we made research in vivo and in vitro systems. And found that bemiparin has a positive effect not only on the coagulation, but also on the rheological properties of blood.

Keywords: Bemiparin, Erythrocyte, Rheology, Microcirculation

Hemorheological, microvascular and hemodynamic disorders during coronary heart disease

57Urdulashvili T., Momtselidze N.,
Mantskava M., Narsia N.,
Mchedlishvili G.


Department of Internal Medicine, State Medical University; Microcirculation Research    Center, I. Beritashvili Institute of Physiology, Tbilisi,  Georgia.

Coronary artery disease (CAD) is the leading cause of cardiovascular mortality worldwide. Even more, it is projected that CAD mortality rates will double from 1990 to 2020, with approximately 82% of the increase attributable to the developing world [5]. Prevention and targeted control of risk factors for CAD could potentially reduce the impact of CAD in the developing world.
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Many scientists indicate the significance of the monitoring of hemorheological patterns during various forms of the ischemic heart disease [2,6]. The increased RBC aggregation was observed in the patients in the following order: unstable angina, acute myocardial inf- arct. The best correlation was observed by integration of large aggregate fraction as a function of shear stress [1].[/su_animate]

Parathyroid gland dysfunction and blood rheological changes in adolescents

56M. Mantskava, S. Beriashvili,
N. Momtselidze, S. Zenaishvili,
M. Nikolaishvili, T. Tupinashvili,
I. Vashakidze

Beritashvili Biomedical Experimental Center,
Georgian David the Builder University.

The thyroid gland disorders are the contributing factors to the development of periodontitis. Despite the lack of works, discussing the hemoreological and calcium, phosphorus homeostasis disorders, resulting in the destruction of the tooth hard tissue mineralization, their authors confirm the unity of the microcirculation disorders and thyroid dysfunction. Our data also confirm this statement. We believe that the imbalance, caused by parathormone, leads to microcirculation disturbances not only locally, but also to all organs and tissues.

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