Monthly Archives: October 2015

Conferences in the future

We provide you with the list of scientific forums dedicated to current topics of and neighboring disciplines. As we have some kind of organizational priorities on the mentioned forums, we receive the applications from the applicants interested in participation, thesis of the original studies. We will assist in publication of the materials, as well as in attending mentioned forums.



8-10th April 2016, Bergamo, Italy.







What determines blood rheological properties?

Hemorheological parameters determine blood rheological properties.

What determines blood rheological status?

1. Hematocrit.

2. Blood viscosity.

3. Еrythrocyte agregability.

4. Erythrocyte deformability.

What is the danger of causing rheological disorders?

[su_spoiler title=”Answer”]

Increased erythrocyte aggregation, decreased erythrocyte deformation, changed hematocrit and plasma viscosity leads to a blockage of capillaries, a slowed down blood flow and develops a capillary stasis. The result is a lack of oxygen. During erythrocyte aggregation erythrocytes may get damaged and an erythrocyte coagulation factor may be developed, which could cause a rheological catastrophe.[/su_spoiler]

My works

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1. Click on corners of the magazine

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2. We address so: we click a mouse for the edge of the book and we wait. Then we clamp a mouse for the edge of the page and without releasing the button of a mouse we drag the page lifting it to the left or lowering in the different sides – we play about as we want. And so on until the end of the book. Then we leaf through the book in the opposite direction.
The book strongly tely therefore wait for effect of browsing of the last page.[/su_animate]

That's all.

Earnest request: not to rumple the book! Oh, as it is required to the author of works for a long time! (Test for sense of humour!) :)

Pleasant viewing!


Study of hemorheological parameters at hemorrhagic shock

19M. Mantskava, N. Momtselidze,
L. Davlianidze.


I.Beritashvili Center I.Beritashvili Center Of Experimental Biomedicine, Tbilisi, Georgia

Nervous system is concerned to be a structure consisted of dynamic glio-neuro-synaptic networks that are able to morphological and functional modulation under external stimuli. Hemorheological shock is a external stimuli and stressor for brain.

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A particular link, which is involved in various stages of hemorheological shock, is blood The aim of our work was a comprehensive rheological properties of blood: red blood cell aggregation, deformation of erythrocytes, plasma viscosity, hematocrit at different degrees of severity of experimental hemorrhagic shock. [/su_animate]

Reological disorders with preeclampsia

17Mantskava M.,  Momtselidze N.

Berlin, Germany, 18-21 Mach, 2016 (16 World Congress on Human Reproduction)

The aim of the present study is comparison of changes of hemorheological functional condition responsible for blood flow disorders in the microcirculation in physiology pregnancy, pregnancy women with preeclampsia and control group. The principal factor of hemoreological was monitored RBC aggregation with the "Georgian technique" that is sensitive and provided us with direct and quantitative data. 

[su_animate type=”slideInLeft”]We investigated 25 subjects with mean age 25,5±3,4 (physiological first pregnancy, 21 weeks, n=10; first pregnancy with preeclampsia, 21 weeks, n=8; control, n=7).[/su_animate] 

Safety of treatment of various diseases

7Davlianidze L., Mantskava M.,
Pargalava N.


The center of experimental biomedicine of I. Beritashvili



[su_animate type=”fadeInLeft”]You will be able to study this article if you pass into the Russian department of the site and click on a tag of "RUS".[/su_animate]


Stress – cause and effect hemorheological disorders

15Mantskava M., Momtselidze N.

Lambert academic  Publishing ISBN 978-3-659-66518-9), 2014  –77 стр.

The book examines various rheological aspects of the different etiology  stress. Hemorrhagic shock occurring at blood loss appears to be a powerful stress for the organism. The origin (emergence) and spread of stress reactions are characterized by the features of the macro-and microcirculation. In stressful situations the crisis of blood circulation affects the functions of hemorheological disorders, as well as appears to be a consequence of the shock. We were the first to combine these two problems.  

There is a maximum possible rate of adaptive energy consumption and at this maximum the organism cannot cope with any additional stimulus. At the same time adaptive and stress diseases develop. Let’s consider the duration and manifestation of Raynaud's disease from the perspective of adaptation diseases and diseases of the third grade, which appears to be the cause of the double stress effect — cold and emotional- physical and psychic.

Sleep apnea is a independent pathology and a powerful stress for the organism. Apnea is a cause of stress and strengthens the body under stress. We propose a new marker for apnea: platelet composes.

Our data in this book have practical significance for biomedicine.

[su_animate type=”tada”]You will be able to study this article if you pass into the Russian department of the site and click on a tag of "RUS".[/su_animate]


Microcirculation, blood rheology status and age-related changes

14Mantskava М., Momtselidze Н.

Bulletin of Medical control center of Affairs of the President of the Republic of Kazakhstan, No. 5, 2015 Materials I of the Euroasian congress of gerontologists. Pp.173-178.
УДК 612.013.1
УДК 612.135

The major link ofpathogeny ofdevelopment ofthe age-related changes is violation ofmicrocirculation and hemorheology. Practically healthy subjects that were subdivided into age-related groups took part in population researches. The 1st group from 35 to 45 (middle age 40.07+4.5, n=15), 2th group from 48 to 55 (middle age 70.6+5.0, n=15). Protocol o f realization o f researches corresponded to Helsinski declaration [2]. All the investigated hemorheology studies: went through the investigated were examined to hemorheologic status o f blood. The o f arespondence o f red corpuscles settled accounts through the apparatus o f texture analysis (Tas- plus, Leitz). In thefirst group the index ofarespondence on “Georgian technique”was equal to 23+4.7%, in the second group to 31+3.3%, in the third group to 34+2.2%, in a fourth group to 36+2.7%. The statistical processing of data showed that in the different age-related groups hemorheologic status differed. был равен 23±4,7%, во второй группе – 31±3,3%, в третьей группе – 34±2,2%, в четвертой группе – 36±2.7%. Violation o f rheological status increased with the increase o f middle age o f subjects, more precisely arespondence of red corpuscles increased as far as growth of middle age in groups age in groups and for certain differedfrom control values. That work showed how much rheological changes are risk-factor of such diseases thatfluctuate with age.


[su_animate type=”shake”] You will be able to study this article if you pass into the Russian department of the site and click on a tag of "RUS".[/su_animate] 


Hemorrhagic shock and stress – cause and effect on the example of violations of hemorheology changes erythrocyte aggregated

75Mantskava M., Momtselidze N.,
Davlianidze L., Mitagvaria N.



The emergence and spread of stress reactions are provided by the blood circulation system. In its turn, the adequacy of blood circulation depends on the hemorheological and vascular mechanisms. The changeability of their properties appears to be the basis of the increasing of stress stages. From the viewpoint of biophysical reactions, any change and movement occur with the expenditure and accumulation of energy.

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Higher level of adaptation energy waste and secondary level take place, when a small stressor entails a small expenditure. There is a maximum possible rate of adaptive energy consumption and at this maximum the organism cannot cope with any additional stimulus.  [/su_animate]

Hemorheological status of blood

12Mantskava M., Momtselidze N.

(ISBN 978-3-659-66111-2) 2014 Lambert academic Publishing.



[su_animate type=”flipInY”]You will be able to study this article if you pass into the Russian department of the site and click on a tag of "RUS".[/su_animate]