Tag Archives: system
Assessment of a functional condition of resistive arteries at the person
G. Mchedlishvili, M. Mantskava,
T. Urdulashvili.
It is notable that the resistance arteries play the leading part in regulation of physiological parameters of the circulation system. It is proposed a new noninvasive method of appraisal of functional state of the human arm resistance arteries. The method is based on research of postischematic hyperemia arising as a result of standard stopping of local blood flow for one minute. The measurement of blood flow velocity in the radial artery of patients is performed by means of ultrasonic device which work is based on Doppler’s effect. For determination of functional state of the resistance arteries a new notion of resistance index is introduced. By this parameter the state of resistance arteries of human arm is investigated at different diseases (Raynaud’s phenomenon, arterial hypertension, diabetes mellitus, etc.).
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The Positive Effect of Bemiparin to Blood Flow in the Experiment (Design research)
Mantskava Maya (Principal Investigator), Assoc.Prof., I.Beritashvili Center of Experimental Biomedicine, Georgia, Tbilisi, 0160, Gotua St., 14, mantskavamaka@rambler.ru; biomedicine.net@gmail.com;
Momtselidze Nana (Investigator), Assoc.Prof., Beritashvili Center of Experimental Biomedicine, Georgia, Tbilisi, 0160, Gotua St., 14;
Davlianidze Lena (Investigator), Assoc.Prof., Beritashvili Center of Experimental Biomedicine, Georgia, Tbilisi, 0160, Gotua St., 14;
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Two different systems that provide motion and movement of blood are involved simultaneously in human body (Kamensky A. and Kamkin A., 2004, ISBN 5-7695-1675-5). This is coagulation/anticoagulation and rheological. Blood is not a homogeneous (Newtonian) liquid and it is a suspension having suspended particles, it has exceptional features and it is studied by coagulation and hemorheology. Coagulation and hemorheology play a significant role in blood circulation and ensure its trophic function. (Hoffman M., Monroe D., 2006). Changes in coagulation and rheological properties of blood may cause a slowdown in the flow, establishment of stasis, thrombus, which is accompanied by multi-disease.[/su_animate]
Coagulation involves the formation of various substances which are produced as a genetically determined body components (primary anticoagulants) or arise in blood clotting and fibrinolysis (secondary anticoagulant).
Role of various stressor in the starting mechanism of an illness of Reynaud (haemo rheological and vascular reactions)
Мantskava M., Momtselidze N.,
Pargalava N.
The emergence and spread of stress reactions are provided by the blood circulation system. In its turn, the adequacy of blood circulation depends on the hemorheological and vascular mechanisms. The changeability of their properties appears to be the basis of the increasing of stress stages. From the viewpoint of biophysical reactions, any change and movement occur with the expenditure and accumulation of energy. Higher level of adaptation energy waste and secondary level take place, when a small stressor entails a small expenditure.
There is a maximum possible rate of adaptive energy consumption and at this maximum the organism cannot cope with any additional stimulus. At the same time adaptive and stress diseases develop. Let’s consider the duration and manifestation of Raynaud’s disease from the perspective of adaptation diseases and diseases of the third grade, which appears to be the cause of the double stress effect – cold and emotional- physical and psychic. Total of 97 patients with Raynaud’s disease were examined. For a new vision of the problem it was necessary to find out how the streessors of various nature impact the hemoreheological status and vascular resistance.
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For this purpose all the patients were examined for a resistance index of resistive arteries of the hand and the indices of erythrocyte aggregation and deformability. The patients were divided into four subgroups. The first subgroup – the patients after chilblain, the second subgroup – the patients with psychic strerssor, the third subgroup – the patients with prolonged chronic stress, and the fourth subgroup – the patients without the differentiation of the stressors. [/su_animate]
Hemorrhagic shock and stress – cause and effect on the example of violations of hemorheology changes erythrocyte aggregated
Mantskava M., Momtselidze N.,
Davlianidze L., Mitagvaria N.
The emergence and spread of stress reactions are provided by the blood circulation system. In its turn, the adequacy of blood circulation depends on the hemorheological and vascular mechanisms. The changeability of their properties appears to be the basis of the increasing of stress stages. From the viewpoint of biophysical reactions, any change and movement occur with the expenditure and accumulation of energy.
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Higher level of adaptation energy waste and secondary level take place, when a small stressor entails a small expenditure. There is a maximum possible rate of adaptive energy consumption and at this maximum the organism cannot cope with any additional stimulus. [/su_animate]
