Tag Archives: studies
Thyroid and periodontitis
Mantskava M.
The modern world is increasing every year the number of people with thyroid dysfunction. It is necessary to pay attention to the children (11-15 yars old). 5% of this population is patient with thyroid dysfunction. At this age, most developing first and second stage of periodontal disease. Population rheological studies suggest that periodontitis when compared with the control hemorheological status is changed to 15%, that thyroid dysfunction when compared with the control hemorheological status is changed to 30%. Rheological status in patients with thyroid dysfunction and periodontal disease is even more variability. The book details shows the effect of the formation periodontal disease during thyroid dysfunction.
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Hemorheological Disorders and Arteriolar Resistance During Ischemic Heart Disease
T. Urdulashvili, N. Momtselidze,
M. Mantskava, N. Narsia,
G. Mchedlishvili.
Microcirculation research Center, I.Beritashvili Institute of Physiology, Tbilisi, Georgia.
Internal Medicine, State medical University, Tbilisi, Georgia.
Abstract. It could be conjectured that the hemorheological disorders are involved in development of the ischemic heart disease. But this fact was so far insufficiently cleared up. The present studies were carried out in patients with various forms of chronic ischemic heart disease. We investigated the most significant factor of rheological disorders in the microcirculation, the erythrocyte aggregability, which a technique that provided us with the direct and quantitative data. Simultaneously we investigated in the some patients the tone of the resistance arteries of the hand with an original non-invasive technique. We found that the erythrocyte aggregability increased almost twice in the blood of investigated patients as compared to the healthy control group. The aggregability was positively correlated with severity of the disease.
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The most pronounced hemorheological disorders were found in the patients with the heart failure. As to the arteriolar resistance index, it was increased only in 45 per cent of all the investigated patients and no significant difference between the patients with the heart failure and without it was found available. We concludes that the blood rheological disorders represent themselves a factor that plays a significant role in pathogenesis of development of the heart disease.[/su_animate]
Resistive arteries, normal function and pathological reactions
Мchedlishvili G., Tsinamdzgvrishvili B., Mantskava M.
Our studies have shown pathogenic resistive functional characteristics of arteries in the body, which provide a normal and an abnormal pressure in microcirculation of organs. Our studies have shown pathogenic characteristics of the functional state of resistive arteries in the body, which provide a normal and an abnormal pressure in microcirculation of organs. Furthermore, our studies have shown changes of тче smooth muscle of resistive arteries, which cause pathological constriction. Based on this data, we developed a technique to determine the functional state of the resistance arteries.
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Hemorheological disorders and arteriolar resistance during ischemic heart disease
T. Urdulashvili., N. Momtselidze.,
M. Mantskava., N. Narsia.,
G. Mchedlishvili.
Clinical hemorheology and microcirculation 2004;30(3-4):399-401.
Abstract
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It could be conjectured that the hemorheological disorders are involved in development of the ischemic heart disease. But this fact was so far insufficiently cleared up. The present studies were carried out in patients with various forms of chronic ischemic heart disease. We investigated the most significant factor of rheological disorders in the microcirculation, the erythrocyte aggregability, with a technique that provided us with the direct and quantitative data.[/su_animate]
Direct beneficial effect of insulin on blood rheological disorders in the microcirculation
M. Mantskava, N. Pargalava,
G. Mchedlishvili.
Clinical hemorheology and microcirculation 2004;30(3-4):431-3.
Abstract
Under both the in vivo and in vitro conditions we investigated the insulin effect on the most significant factor disturbing the blood rheological disorders in the microcirculation, the red blood cell aggregability.
[su_animate type=”slideInRight”]The in vivo studies we carried out in the 42 insulin treated diabetic patients (diabetes mellitus type II), as well as conducted the in vitro investigations of the blood both of the diabetic patients (24) and of the healthy people (20) where the insulin was added to the blood ex vivo. The RBC aggregability in blood investigated with the “Georgian technique” was found significantly enhanced, by about 100 per cents in the diabetic patients.[/su_animate]
Bood hemorheological status Bood hemorheological status during arterial hypertension
M. Mantskava, N. Momtselidze.
Microcirculation is an important part of blood flow. It provides adequacy of blood suppy in organs and tissues. The newset method of biomedicine is a joint study of microcirculation and hemoreology. There is no pathologycal preocess where homoreological studies are not informative. Studies, data and conclusions persented in the book confirm the necessity of studying rheological features during arterial hypertansion treatment.
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