Tag Archives: Stress
Hemorrhagic Shock and Stress – Cause and Consequence of Hemorheology Disturbances on the Example of the Changes in Erythrocyte Aggregation
Mantskava M., Momtselidze N.,
Davlianidze N., Mitagvaria N.
I. Beritashvili Center for Experimental Biomedicine, Department of Blood Circulation and Metabolism,Tbilisi, Georgia, 0160.
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Stress, being the general reaction of the organism to the physical and psychological effects, accompanies all the
stages of somatic and psychic formation. Hemorrhagic shock occurring at blood loss appears to be a powerful stress for the organism. The origin (emergence) and spread of stress reactions are characterized by the features of the macro-and microcirculation. In stressful situations the crisis of blood circulation affects the functions of hemorheological disorders, as well as appears to be a consequence of the shock. We were the first to combine these two problems.[/su_animate]
The Role of Various Stressors in the Trigger Mechanism of Raynaud’s Disease (Hemorheological and Vascular Reactions)
Mantskava M., Momtselidze N.,
Pargalava N.
I. Beritashvili Center for Experimental Biomedicine, Department of Blood Circulation and Metabolism, Tbilisi, Georgia, 0160.
Acad. N. Bokhua Center of Vascular and Heart Diseases, Tbilisi, Georgia, 0159.
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The emergence and spread of stress reactions are provided by the blood circulation system. In its turn, the adequacy of blood circulation depends on the hemorheological and vascular mechanisms. The changeability of their properties appears to be the basis of the increasing of stress stages. From the viewpoint of biophysical reactions, any change and movement occur with the expenditure and accumulation of energy. Higher level of adaptation energy waste and secondary level take place, when a small stressor entails a small expenditure. There is a maximum possible rate of adaptive energy consumption and at this maximum the organism cannot cope with any additional stimulus.[/su_animate]
Assessment of Platelet in Case of Stress-induced Apnea
Mantskava M.M., Momtselidze N.G.
I. Beritashvili Center for Experimental Biomedicine, Department of Blood Circulation and Metabolism,
Tbilisi, Georgia, 0160
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Sleep apnea is a independent pathology and a powerful stress for the organism. Apnea is a cause of stress and strengthens the body under stress. We studied 30 men aged 34 to 57 years: 22 patients with obstructive sleep apnea and 8 patients with central sleep apnea. We explored a drop of blood in HUMACOUNT, mod. HUMACOUNT (Firm Human GmbH, Germany), bought of grant budget RF/420/7-270/12. We investigated parameters of platelet: PLT, MPV, PDWс and PCT. The analysis of the data was performed using statistical programs “Origin 4.1’’ (Microsoft. Software, Inc) and Microsoft Excel, evaluated Student and criteria Pearson.[/su_animate]
Role of various stressor in the starting mechanism of an illness of Reynaud (haemo rheological and vascular reactions)
Мantskava M., Momtselidze N.,
Pargalava N.
The emergence and spread of stress reactions are provided by the blood circulation system. In its turn, the adequacy of blood circulation depends on the hemorheological and vascular mechanisms. The changeability of their properties appears to be the basis of the increasing of stress stages. From the viewpoint of biophysical reactions, any change and movement occur with the expenditure and accumulation of energy. Higher level of adaptation energy waste and secondary level take place, when a small stressor entails a small expenditure.
There is a maximum possible rate of adaptive energy consumption and at this maximum the organism cannot cope with any additional stimulus. At the same time adaptive and stress diseases develop. Let’s consider the duration and manifestation of Raynaud’s disease from the perspective of adaptation diseases and diseases of the third grade, which appears to be the cause of the double stress effect – cold and emotional- physical and psychic. Total of 97 patients with Raynaud’s disease were examined. For a new vision of the problem it was necessary to find out how the streessors of various nature impact the hemoreheological status and vascular resistance.
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For this purpose all the patients were examined for a resistance index of resistive arteries of the hand and the indices of erythrocyte aggregation and deformability. The patients were divided into four subgroups. The first subgroup – the patients after chilblain, the second subgroup – the patients with psychic strerssor, the third subgroup – the patients with prolonged chronic stress, and the fourth subgroup – the patients without the differentiation of the stressors. [/su_animate]
Blood rheological status in obstruction apnea
M. Mantskava, G. Azikuri,
N. Momtselidze, N. Mitagvaria.
I. Beritashvili Center for Experimental Biomedicine, Tbilisi, Georgia
Summary
Sleep apnea is an independent pathology and a powerful stress for the organism. Apnea affects different systems. 44 patients with obstructive apnea (age 45.4±5 years) were under observation. Control group consisted of healthy subjects aged 36.3±5 years. Rheological status in the group of patients was as follows: RBC aggregability index – 42.7±7.2, RBC deformability index was 2.23±0.06, plasma viscosity – 1.27±0.03 and Hct – 39±5. The same parameters in the control group were: RBC aggregability index – 25.0±3.0, RBC deformability index – 2.23±0.02, plasma viscosity – 1.25±0.02, Hct – 45±3. The obtained data allow to recommend clinicians include disaggregants in standard treatment of obstructive sleep apnea.
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Stress – cause and effect hemorheological disorders
Mantskava M., Momtselidze N.
Lambert academic Publishing ISBN 978-3-659-66518-9), 2014 www.lap-publishing.com –77 стр.
The book examines various rheological aspects of the different etiology stress. Hemorrhagic shock occurring at blood loss appears to be a powerful stress for the organism. The origin (emergence) and spread of stress reactions are characterized by the features of the macro-and microcirculation. In stressful situations the crisis of blood circulation affects the functions of hemorheological disorders, as well as appears to be a consequence of the shock. We were the first to combine these two problems.
There is a maximum possible rate of adaptive energy consumption and at this maximum the organism cannot cope with any additional stimulus. At the same time adaptive and stress diseases develop. Let’s consider the duration and manifestation of Raynaud’s disease from the perspective of adaptation diseases and diseases of the third grade, which appears to be the cause of the double stress effect — cold and emotional- physical and psychic.
Sleep apnea is a independent pathology and a powerful stress for the organism. Apnea is a cause of stress and strengthens the body under stress. We propose a new marker for apnea: platelet composes.
Our data in this book have practical significance for biomedicine.
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Hemorrhagic shock and stress – cause and effect on the example of violations of hemorheology changes erythrocyte aggregated
Mantskava M., Momtselidze N.,
Davlianidze L., Mitagvaria N.
The emergence and spread of stress reactions are provided by the blood circulation system. In its turn, the adequacy of blood circulation depends on the hemorheological and vascular mechanisms. The changeability of their properties appears to be the basis of the increasing of stress stages. From the viewpoint of biophysical reactions, any change and movement occur with the expenditure and accumulation of energy.
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Higher level of adaptation energy waste and secondary level take place, when a small stressor entails a small expenditure. There is a maximum possible rate of adaptive energy consumption and at this maximum the organism cannot cope with any additional stimulus. [/su_animate]
