Tag Archives: organism
Hemorrhagic Shock and Stress – Cause and Consequence of Hemorheology Disturbances on the Example of the Changes in Erythrocyte Aggregation
Mantskava M., Momtselidze N.,
Davlianidze N., Mitagvaria N.
I. Beritashvili Center for Experimental Biomedicine, Department of Blood Circulation and Metabolism,Tbilisi, Georgia, 0160.
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Stress, being the general reaction of the organism to the physical and psychological effects, accompanies all the
stages of somatic and psychic formation. Hemorrhagic shock occurring at blood loss appears to be a powerful stress for the organism. The origin (emergence) and spread of stress reactions are characterized by the features of the macro-and microcirculation. In stressful situations the crisis of blood circulation affects the functions of hemorheological disorders, as well as appears to be a consequence of the shock. We were the first to combine these two problems.[/su_animate]
Assessment of Platelet in Case of Stress-induced Apnea
Mantskava M.M., Momtselidze N.G.
I. Beritashvili Center for Experimental Biomedicine, Department of Blood Circulation and Metabolism,
Tbilisi, Georgia, 0160
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Sleep apnea is a independent pathology and a powerful stress for the organism. Apnea is a cause of stress and strengthens the body under stress. We studied 30 men aged 34 to 57 years: 22 patients with obstructive sleep apnea and 8 patients with central sleep apnea. We explored a drop of blood in HUMACOUNT, mod. HUMACOUNT (Firm Human GmbH, Germany), bought of grant budget RF/420/7-270/12. We investigated parameters of platelet: PLT, MPV, PDWс and PCT. The analysis of the data was performed using statistical programs “Origin 4.1’’ (Microsoft. Software, Inc) and Microsoft Excel, evaluated Student and criteria Pearson.[/su_animate]
Blood rheological status in obstruction apnea
M. Mantskava, G. Azikuri,
N. Momtselidze, N. Mitagvaria.
I. Beritashvili Center for Experimental Biomedicine, Tbilisi, Georgia
Summary
Sleep apnea is an independent pathology and a powerful stress for the organism. Apnea affects different systems. 44 patients with obstructive apnea (age 45.4±5 years) were under observation. Control group consisted of healthy subjects aged 36.3±5 years. Rheological status in the group of patients was as follows: RBC aggregability index – 42.7±7.2, RBC deformability index was 2.23±0.06, plasma viscosity – 1.27±0.03 and Hct – 39±5. The same parameters in the control group were: RBC aggregability index – 25.0±3.0, RBC deformability index – 2.23±0.02, plasma viscosity – 1.25±0.02, Hct – 45±3. The obtained data allow to recommend clinicians include disaggregants in standard treatment of obstructive sleep apnea.
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