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Hemorheological, microvascular and hemodynamic disorders during coronary heart disease

57Urdulashvili T., Momtselidze N.,
Mantskava M., Narsia N.,
Mchedlishvili G.

 

Department of Internal Medicine, State Medical University; Microcirculation Research    Center, I. Beritashvili Institute of Physiology, Tbilisi,  Georgia.

Coronary artery disease (CAD) is the leading cause of cardiovascular mortality worldwide. Even more, it is projected that CAD mortality rates will double from 1990 to 2020, with approximately 82% of the increase attributable to the developing world [5]. Prevention and targeted control of risk factors for CAD could potentially reduce the impact of CAD in the developing world.
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Many scientists indicate the significance of the monitoring of hemorheological patterns during various forms of the ischemic heart disease [2,6]. The increased RBC aggregation was observed in the patients in the following order: unstable angina, acute myocardial inf- arct. The best correlation was observed by integration of large aggregate fraction as a function of shear stress [1].[/su_animate]