Tag Archives: diabetes
Hemorheological disorders during ischemic brain infarcts in patients with and without diabetes mellitus
N. Momtselidze., M. Mantskava.,
G. Mchedlishvili.
Clinical hemorheology and microcirculation 2006;35(1-2):261-4.
Abstract
[su_animate type=”tada”]
The aim of the present study was the comparative analysis of the role of specific hemorheological derangements in the pathogenesis of ischemic brain infarcts with and without diabetes mellitus. Blood plasma viscosity, as well as red blood cells (RBC) aggregability were quantitatively investigated in all patients during the study. Both of the above mentioned indices of hemorheological disorders were significantly higher in the patients with brain infarcts and diabetes mellitus as compared to the control and the group of ischemic brain infarcts without diabetes.[/su_animate]
Hemorheological disorders in patients with type 1 or 2 diabetes mellitus and foot gangrene
Maya Mantskava, Nana Momtselidze, Nugzar Pargalava, George Mchedlishvili.
Microcirculation Research Center, I. Beritashvili Institure of Physiology, 14 Gotua St., 0160, Tbilisi, Georgia
N. Bochua Center of Angiology and Vascular Surgery, 1. Chachava St., 0159, Tbilisi, Georgia
Abstract. The aim of the present study was to evaluate blood rheological disorders, in particular RBC enhanced aggregation, and compare changes in these parameters in patients with type I and II diabetes mellitus. For evaluation of RBC aggregability in the present study we applied the “Georgian technique”, which was developed and applied for several years in our laboratory. Its advantage is that it is a direct and quantitative method. In all the investigated patients, diabetes mellitus was compared with the foot gangrenes. The patients were divided into two groups: (a) with type I and with type II diabetes mellitus. We matched the RBC aggregability indices in both groups of diabetic patients and compared the obtained results with those in the healthy control group. We found that rheological disorders were considerably pronounced.
[su_animate type=”fadeInLeft”]
The RBC aggregability index increased by 62 per cent (p<0.001) in type I and by 57 per cent (p<0.001) in type II diabetic patients as compared to the control group. However, there were insignificant differences of the RBC aggregability changes between the two groups of the patients. Therefore we conclude that blood rheological disorders are similar in both types of diabetes mellitus. The disturbed blood fluidity related to the increased RBC aggregability in the microcirculation promotes, in particular, the development of the gangrene in both types of diabetes mellitus.Text[/su_animate]
Influence ofdifferent types of insulin on the aggregation of red blood cells in patients with diabetes
Mantskava М., Momtselidze Н.
The center of Experimental Biomedicine of I. Beritashvili,
Department of microcirculation and haemo rheology.biz, 0160, Georgia, Tbilisi, ul. L. Gotua, 14.
[su_animate type=”flipInY”]You will be able to study this article if you pass into the Russian department of the site and click on a tag of “RUS”.[/su_animate]
